Found 14 matching trials
Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants
PHASE3Open-Label Extension and Safety Monitoring Study of Acoramidis (AG10) in Pa...
Status
Active Not Recruiting
Location
Cedars-Sinai Medical Center
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
PHASE4The study aims to evaluate the effect of acoramidis on cardiac functional a...
Location
Washington University in St. Louis
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
PHASE3Transthyretin amyloidosis (ATTR) is a disease where the normally occurring ...
Location
University of California, San Diego (UCSD) - Medical Center
Open-Label Study of AG10 in Patients with Cardiomyopathy
PHASE2This prospective, multicenter open-label study will evaluate the long-term ...
Status
Active Not Recruiting
Location
Stanford University
Efficacy and Safety of AG10 in Subjects with Transthyretin Amyloid Polyneurophathy
PHASE3See updated study design under NCT04882735. Phase 3 efficacy and safety of ...
Location
Eidos Therapeutics
A Single Dose Study to Evaluate the Pharmacokinetics of Acoramidis Modified Release Formulations in Healthy Subjects
PHASE1This is a single centre, open-label, 5-period study in healthy male and non...
Location
Quotient Sciences
A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM
PHASE3This prospective study is designed to evaluate the efficacy, safety, and to...
Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy
PHASE3Phase 3 efficacy and safety study to evaluate acoramidis (AG10) HCl 800 mg ...
Location
Cedars-Sinai Medical Center
To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)
PHASE3The AG10-504 study is an open-label extension study of acoramidis in partic...
Location
Multiple Locations
Efficacy and Safety of Acoramidis (AG10) in Subjects with Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)
PHASE3Phase 3 efficacy and safety of acoramidis in subjects with symptomatic Tran...
Location
Multiple Locations