Found 49 matching trials
A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients PHASE1 This is a 2-part, open-label, interventional study conducted in approximate...
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Local Institution - 103
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Phase 1/2 Study of Enasidenib (AG-221) in Adults With Advanced Hematologic Malignancies With an Isocitrate Dehydrogenase Isoform 2 (IDH2) Mutation PHASE1 The primary objectives of Phase 1 Dose Escalation/Part 1 Expansion are:
* ...
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IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study) PHASE2 This phase II study compares the order of treatment with ivosidenib or enas...
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University of Colorado
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Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors PHASE2 Background:
Cancers of the nasal cavity or skull base are rare. They often...
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National Institutes of Health Clinical Center
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A Study to Assess the Pharmacokinetics of Enasidenib (CC-90007) in Subjects With Moderate and Severe Hepatic Impairment. PHASE1 This is a multi-center, open-label study to assess the PK of single 100 mg ...
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DaVita Clinical Research
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IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation PHASE1 This research study is studying a targeted therapy drug as a possible treat...
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Johns Hopkins Cancer Center
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Radiolabeled Study of AG-221 in Healthy Male Subjects. PHASE1 This is a single-center, 2-part, open-label study to evaluate the metabolis...
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Multiple Locations
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Bioavailability of Enasidenib (CC-90007) Sprinkle Formulation Relative to the Reference Tablet Formulation and Effect of Food on the Pharmacokinetics of Sprinkle Formulation in Healthy Adults PHASE1 This is an open-label, single-center, randomized, three-period, two-sequenc...
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PPD Development, LP
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Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial) PHASE2 This phase II MyeloMATCH treatment trial studies how well ASTX727 and venet...
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Banner University Medical Center - Tucson
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Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutation PHASE1 This is a phase 1b/2, open-label, single arm study to evaluate if enasideni...
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Stanford Cancer Institute
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