Found 28 matching trials
Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing Chorea PHASE2 This study will assess the efficacy, safety and tolerability of AFQ056 when...
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Novartis Investigator Site
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Effects of AFQ056 and Baclofen on Meal-Induced Gastroesophageal Reflux PHASE1 This study will assess the safety and tolerability of oral single dose appl...
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Novartis Investigative site
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Evaluation of the Efficacy and Safety of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias PHASE2 This study will assess the efficacy and safety of AFQ056 in patients that h...
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Novartis Investigative Site
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Metabotropic Glutamate Receptor-5 (mGlur5) Effects on Reward-Related fMRI-BOLD Activation in FHP and FHN EARLY_PHASE1 The purpose of this pilot study is to evaluate the role of Mavoglurant in c...
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Hartford Hospital
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Effects of AFQ056 and Nicotine in Reducing Cigarette Smoking PHASE1 The purpose of this study is to assess the safety and efficacy of AFQ056 an...
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Novartis Investigative Site
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Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD) PHASE2 This study assessed whether AFQ056 had a beneficial effect by reducing coca...
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Novartis Investigative Site
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An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects PHASE1 The aim of this study was to characterize the pharmacokinetics and safety o...
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Novartis Investigative Site
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Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias PHASE2 This study is to evaluate long-term safety, tolerability and efficacy for A...
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Novartis Investigative Site
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A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects PHASE1 This study will assess the pharmacokinetics of AFQ056 in subjects with mild...
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Novartis Investigative Site
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Efficacy and Safety of AFQ056 in Reducing L-dopa Induced Dyskinesias in Parkinson's Disease Patients, and Safety in Combination With L-dopa PHASE2 This study will evaluate the safety and efficacy of administration of AFQ05...
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Novartis Investigator Site
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