Found 21 matching trials
Study of AEB071 (a Protein Kinase C Inhibitor) in Patients With CD79-mutant Diffuse Large B-Cell Lymphoma PHASE1 This study has two phases, a dose escalation phase and a dose expansion pha...
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City of Hope National Medical Center
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A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis PHASE2 This study is designed to provide efficacy and safety data of several doses...
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Burke Pharmaceutical Research
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Efficacy, Safety and Tolerability of AEB071 Versus Cyclosporine in the Novo Renal Transplant Recipients PHASE2 This study will assess safety and efficacy of AEB071 combined with everolim...
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Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-tacrolimus in de Novo Liver Transplant Patients PHASE2 This study will assess the safety and efficacy of different doses of sotras...
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Novartis Investigative Site
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Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, Prolymphocytic Leukemia, or Richter's Transformation PHASE2 This phase II trial studies how well sotrastaurin acetate works in treating...
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Multiple Locations
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Trial of AEB071 in Combination With BYL719 in Patients With Melanoma PHASE1 Primary objective is to define the maximum tolerated dose (MTD) for the com...
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Bascom Palmer Eye Institute of University Of Miami Medical Center
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Study of Neoadjuvant RBP-01 In Patients With Primary Uveal Melanoma PHASE1 Neoadjuvant RBP-01 in patients with primary uveal melanoma....
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Multiple Locations
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Safety of AEB071 in Healthy Volunteers and to Compare the Ethnicity, Metabolic, and Safety Effects Between Caucasian and Japanese Healthy Subjects PHASE1 This is a study to assess the safety effects after multiple doses of AEB071...
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Novartis Investigative Site
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Safety, Tolerability, and Efficacy of AEB071 in the Treatment of Uveitis PHASE2 The purpose of this study is to assess the safety, tolerability, and effica...
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University of Southern California Doheny Eye Institute
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Efficacy, Safety and Tolerability of AEB071 in Patients With Active, Moderate to Severe Ulcerative Colitis PHASE2 This study will evaluate the efficacy, safety and tolerability of AEB071 in...
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Novartis Investigative Site
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