Found 23 matching trials
A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin PHASE1 A study in healthy male subjects to investigate whether administration of A...
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A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects PHASE1 So far, ACT-541468 has been studied mainly in Caucasian subjects. The prese...
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Centre for Human Drug Research
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A Single Ascending Dose Study of ACT-541468 in Healthy Male Subjects PHASE1 The main objectives of this first-into-man study were to investigate the sa...
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A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease PHASE1 A study to evaluate the effects of ACT-541468 on respiration in patients wi...
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Advanced Sleep Research
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A Clinical Study to Assess Next-day Driving Performance Following Administration of ACT-541468 in Middle-aged and Elderly Subjects PHASE1 A clinical study to assess next-day driving performance following evening a...
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Centre for Human Drug Research
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Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia Disorder PHASE2 This study evaluates the dose response of ACT-541468 on the change of wake ...
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Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder PHASE3 The main purpose of this study is to assess efficacy and safety of ACT-5414...
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Pinnacle Research Group, LLC
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A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects PHASE1 The purpose of this study is to evaluate the tolerability, safety, pharmaco...
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A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep Apnea PHASE1 This study is conducted to investigate the effects of ACT-541468 on nightti...
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Advanced Sleep Research
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A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and Midazolam PHASE1 The main objectives of this phase 1 trial are to evaluate the effect of foo...
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