Found 11 matching trials
A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-132577 Can Affect Rosuvastatin's Fate in the Body (Amount and Time of Presence in the Blood) PHASE1 The primary purpose of this study is to investigate the effect of Aprociten...
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A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease. PHASE3 The purpose of this research study is to show the blood pressure lowering e...
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Multiple Locations
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Clinical Study to Assess Body Fluid Homeostasis After Administration of ACT-132577 in Healthy Subjects PHASE1 This clinical study will be conducted to evaluate the effect of ACT-132577 ...
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Investigator Site Lausanne
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Bioequivalence Study of Different Aprocitentan Tablet Formulations PHASE1 The main purpose is to study the pharmacokinetics of aprocitentan (ACT-1325...
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To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women PHASE1 To demonstrate that multiple-dose administration of oral therapeutic and su...
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CRS Clinical Research Services Mannheim GmbH
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A Study to Investigate the Effect of ACT-132577 on the Pharmacokinetics of Midazolam and 1-hydroxy Midazolam in Healthy Male Subjects PHASE1 The purpose of this study is to evaluate the effect of ACT-132577 on the ph...
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Investigator Site
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A Study to Evaluate ACT-132577 in Healthy Male Subjects PHASE1 The primary purpose of this study is to investigate the rate and routes (ur...
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PRA Health Sciences
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A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease PHASE1 The primary purpose of this study is to investigate the fate of ACT-132577 ...
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Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential Hypertension PHASE2 The main objective will be to evaluate the dose-response of ACT-132577 (apr...
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Appalachian Cardiovascular Associates
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A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety PHASE3 The goal of this clinical trial is to show the blood pressure lowering effe...
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Advanced Cardiovascular, LLC
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