Found 22 matching trials
A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)
PHASE2The purpose of this study is to evaluate the long-term safety and efficacy ...
Location
Clinical Trial Site
A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN
PHASE2The primary objective of this study was to determine whether ACH-0144471 (a...
Location
Clinical Trial Site
Study of Danicopan in Participants With Hepatic Impairment
PHASE1The purpose of this study was to evaluate the safety, tolerability, and pha...
Location
Clinical Trial Site
Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)
PHASE2The purpose of this study was to determine the safety and efficacy of ACH-0...
Location
Clinical Trial Site
A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants
PHASE1The purpose of this study was to determine the potential drug interaction b...
Location
Clinical Trial Site
A Study of the Cardiac Effects of Danicopan in Healthy Adults
PHASE1This was a randomized, double-blind, double-dummy, placebo- and positive-co...
Location
Clinical Trial Site
A Drug Interaction Study of Danicopan
PHASE1This was a 3-part study (Part 1, Part 2, Part 3) with each part being an op...
Location
Clinical Study Site
A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults
PHASE1This was a 3-part study with each part being an open-label, fixed-sequence,...
Location
Clinical Trial Site
A Study of the Effects of Food and Age on Danicopan
PHASE1This will be an open-label, 2-part study. Part 1 will be a randomized, 2-se...
Location
Clinical Trial Site
Study of Danicopan in Participants of Japanese Descent
PHASE1This study will assess the safety, tolerability, pharmacokinetics (PK), and...
Location
Clinical Study Site