Found 11 matching trials
Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer PHASE2 This study will evaluate the safety and effectiveness of a combination of s...
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Columbia University Irving Medical Center / NewYork-Presbyterian Hospital
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A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies PHASE1 This is a Phase 1, open-label, dose-escalation, and dose-expansion, with a ...
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Active Not Recruiting
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Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer PHASE1 This phase Ib/II trial tests the safety, side effects, and best dose of que...
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Fred Hutch/University of Washington Cancer Consortium
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A Study to Investigate the Pharmacokinetic Profile of Oral AB680 in Healthy Volunteers PHASE1 A Double-Blind, Randomized, Placebo-Controlled, Single Ascending Dose Study...
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A Study to Investigate the Safety of AB680 in Healthy Volunteers PHASE1 This is a double-blind, randomized, placebo-controlled, single- and multipl...
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Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma PHASE1 This phase I/II study tests how well zimberelimab and quemliclustat work in...
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An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer. PHASE1 This randomized phase 1b/2 open-label study will evaluate the antitumour ac...
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Arizona Clinical Research Center Inc
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Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer PHASE1 This is a Phase 1b/2, open-label, multicenter platform trial to evaluate th...
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The Oncology Institute of Hope & Innovation
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Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma PHASE2 The purpose of this study is to combine standard radiation therapy with dru...
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Northwell Health R.J. Zuckerberg Cancer Center
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Metabolism, Excretion, and Mass Balance Study of Quemliclustat in Healthy Adult Participants (ARC-24) PHASE1 The purpose of the study is to investigate the routes of elimination and ov...
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