Found 19 matching trials
To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers
PHASE1Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
Selumetinib in Combination With Gefitinib in NSCLC Patients
PHASE1This is an open-label, non-randomized, multicenter phase Ib/II study, which...
Location
National Cheng Kung University Hospital
To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
PHASE1Study to assess the effect of Rifampicin on the pharmacokinetics of Selumet...
Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study
PHASE1The objective of this study is to investigate the safety and tolerability o...
Location
AZD6244 PhI Japanese Gem/
Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial
PHASE1To determine the maximum tolerated dose (MTD) of AZD6244 or AZD2171 when co...
Location
The Christie NHS Foundation Trust
A Study of Selumetinib in Patients With Kaposi's Sarcoma
PHASE1Cancer is a leading cause of death in individuals living with human immunod...
Location
Brighton and Sussex University Hospitals
A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers
PHASE1A Study to assess, against a reference selumetinib capsule, if the drug lev...
Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec
PHASE2The purpose of this study is to determine whether treatment with Selumetini...
Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)
PHASE3Selumetinib therapy in patients with metastatic uveal melanoma....
Study to Assess the Effect of Dosing AZD6244 HydSulfate in the Presence and Absence of Food in Patients With Advanced Solid Malignancies
PHASE1The purpose of this study is to test if the levels of AZD6244 in blood are ...