Found 42 matching trials
Study to Evaluate the Safety and Efficacy of Phenoptin™ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels
PHASE3The primary objective of this study is to evaluate the efficacy of Phenopti...
Location
Multiple Locations
Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria
PHASE3This is an open-label, non-comparative, Phase 3 study to evaluate the degre...
Location
Please contact Merck KGaA Communication Center
Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response
PHASE2The investigators will investigate the effect of blood phenylalanine on Kuv...
Location
Department of Biochemistry & Molecular Biology
Effect of Kuvan on Neurocognitive Function, Blood Phenylalanine Level, Safety, and Pharmacokinetics in Children With PKU
PHASE3This multicenter, open label study is designed to evaluate the safety of Ku...
Location
Multiple Locations
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
NAMore patients with chronic obstructive pulmonary disease (COPD) die from ca...
Location
Augusta University
Evaluation of BH4 Responsiveness in Our PKU Patients
PHASE1This study aims to evaluate BH4 responsiveness in our PKU patients and to c...
Status
Active Not Recruiting
Location
Sohag Faculty of Medicine
The Effectiveness of Kuvan in Amish PKU Patients
PHASE4The purpose of this study is to determine if Amish patients with PKU show r...
Location
University Hospitals Cleveland Medical Center
O2 Transport and Utilization in Health and Lung Disease
PHASE1Skeletal muscle dysfunction is a frequent and clinically relevant systemic ...
Location
Institute of Applied Life Sciences
The Effect of Antioxidants on Skin Blood Flow-BH4
PHASE1The goal of this study is to examine possible mechanisms of heightened vaso...
Location
Engineering Research Building
Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy
NAThe aim of this pilot study is to determine if there are any changes in bra...
Location
Children's Hospital of Philadelphia, Section of Metabolism,PKU program