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Trial Search

Current Search Criteria:

Intervention: 009-2

Found 39 matching trials

Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)

PHASE1

This study will evaluate the safety, MTD and/or RP2D, PK, and clinical acti...

Status

Terminated

Location

Local Institution - 019-104

Start Date

2023-08-07

Trial ID

NCT05840510

Treatments Being Tested

Adagrasib nab-Sirolimus

TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single Oral Doses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected Patients

PHASE1

The purpose of this study is to assess the safety and tolerability of TMC64...

Status

Completed

Location

Multiple Locations

Start Date

2010-04

Trial ID

NCT01202825

Treatments Being Tested

TMC647055 Placebo TMC647055 TMC647055 Placebo TMC435 Placebo TMC647055 Placebo TMC647055

A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009)

PHASE1

This study is being done to evaluate the antihypertensive efficacy and tole...

Status

Completed

Location

Multiple Locations

Start Date

2011-06-15

Trial ID

NCT01370655

Treatments Being Tested

MK-7145 Hydrochlorothiazide (HCTZ)Placebo to MK-7145 Placebo to HCTZ

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

PHASE3

The purpose of this study is to evaluate sacituzumab tirumotecan versus pem...

Status

Active Not Recruiting

Location

Kaiser Permanente - Oakland ( Site 0054)

Start Date

2024-06-11

Trial ID

NCT06305754

Treatments Being Tested

Sacituzumab tirumotecan Pemetrexed Carboplatin H1 Receptor Antagonist H2 Receptor Antagonist Acetaminophen (or equivalent)Dexamethasone (or equivalent)Steroid Mouthwash (dexamethasone or equivalent)

Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer (8669-009)

PHASE2

This clinical trial will study the use of ridaforolimus in metastatic breas...

Status

Completed

Location

Multiple Locations

Start Date

2008-07

Trial ID

NCT00736970

Treatments Being Tested

ridaforolimus trastuzumab

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

PHASE1

This phase I trial studies the side effects and best dose of nanoparticle a...

Status

Completed

Location

Children's Hospital of Alabama

Start Date

2017-08-15

Trial ID

NCT02975882

Treatments Being Tested

Irinotecan Hydrochloride Laboratory Biomarker Analysis Pharmacological Study Sirolimus Albumin-bound Nanoparticles Temozolomide

A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls

PHASE4

The primary objective of this study is to compare the effect of two differe...

Status

Terminated

Location

Multiple Locations

Start Date

2009-09

Trial ID

NCT00934635

Treatments Being Tested

Paliperidone ER Oral risperidone PET Scan Oral risperidone Oral risperidone Paliperidone ER Paliperidone ER Oral risperidone Paliperidone ER

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

The researchers think that the use of advanced MR imaging may help people w...

Status

Recruiting

Location

Memorial Sloan Kettering Cancer Center

Start Date

2009-03

Trial ID

NCT00870129

Treatments Being Tested

MRI and advanced MRI sequences

A Clinical Study of MK-4482 in Chinese Healthy Male Participants (MK-4482-009)

PHASE1

The goal of the study is to learn what happens to MK-4482 after single and ...

Status

Completed

Location

Peking University Third Hospital (Site 0001)

Start Date

2023-06-28

Trial ID

NCT06816030

Treatments Being Tested

MK-4482

A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)

PHASE2

This study assessed the safety and efficacy of MK-3577. The primary efficac...

Status

Terminated

Location

Multiple Locations

Start Date

2009-03-24

Trial ID

NCT00868790

Treatments Being Tested

MK-3577 Placebo to MK-3577 Metformin Placebo to Metformin

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